Semen: Men’s Chemical War Against Women. Appendix: Compounds in Human Semen Which Alter Female Psychology, Behavior, and Physiology.

No-Skip Intro here. Part I here. Part II here. Part III here. Part IV here. Part V here.

 

Table Source: R.L. Burch and G.G.Gallup,

“The Psychobiology of Sperm,” Cambridge University Press.

 

COMPOUND LEVEL (ng/l) SOURCE EFFECT ON FEMALE
Cholesterol 6148 Valsa et al. (1992) Steroid hormone precursor.
Cortisol 63 700 Brotherton (1990a) Increase approach behaviors, parental care, affection.
Cortisol 20 000 Abbaticchio et al. (1981)
Transcortin 12 000 000 Brotherton (1990a) Stress response, accentuate dopamine effects, increases oxytocin, corticotropin-releasing hormone, and opioids.
Testosterone 500 Hampl et al. (2000) Sexual drive.
Testosterone 559 Asch et al. (1984)
Dihydrotestosterone 695 Asch et al. (1984)
5a-Dihydrotestosterone 300 Hampl et al. (2000)
Androstenedione 2018 Kwan et al. (1992) Precursor to other steroids, immunological properties.
5a-Androst-16-en-3a-ol 600 Kwan et al. (1992) Precursor to other steroids, immunological properties.
5a-Androst-16-en-3-ol 600 Kwan et al. (1992) Precursor to other steroids, immunological properties.
5,16-Androstadien-3-ol 600 Kwan et al. (1992) Precursor to other steroids, immunological properties.
5a-Androst-16-en-3-one 800 Kwan et al. (1992) Precursor to other steroids, immunological properties.
4,16-Androstadien-3-one 800 Kwan et al. (1992) Precursor to other steroids, immunological properties.
7a-Dihydroxy-5-androsten-17-one 1808.18 Hampl et al. (2000) Precursor to other steroids, immunological properties.
7-Dihydroxy-5-androsten-17-one 1694.97 Hampl et al. (2000) Precursor to other steroids, immunological properties.
Estrone 157 Ney (1986) Trigger ovulation, elevate mood, vaginal lubrication,absorption of hormones, pheromone production.
Estradiol 70.2 Ney (1986)
Estradiol 46.9–91.3 Luboshitzky et al. (2002)
Follicle-stimulating hormone 8 500 000 Ney (1986) Steroidogenesis, egg development, ovulation.
Luteinizing hormone 220 000 000 Ney (1986) Steroidogenesis, egg development, ovulation, sex drive.
Luteinizing-releasing hormone 31–71 Chan & Tang (1983) Induces luteinizing hormone release.
Prolactin 86 000 Ney (1986) Antidepressant, facilitates pregnancy, maternal behavior, appetite, oxytocin secretion, and ACTH secretion.
Prolactin 7500 Aiman et al. (1988)
19-Hydroxyprostaglandin E Kelly (1995) Immunosuppressant.
Prostaglandin E1 Ney (1986), Kelly (1995) Uterine contractions, ovulation.
Prostaglandin E2 Ney (1986), Kelly (1995) Uterine contractions, ovulation.
Prostaglandin F2 Ney (1986) Uterine contractions, ovulation.
Oxytocin 1.72 Goverde et al. (1998) Increases testosterone, prostaglandins, involved in orgasm, affiliation and bonding, elevates mood.
Vasopressin 1.84 Brotherton (1990c) Arousal, attention, vigilance, sympathetic function.
Thyrotropin-releasing hormone 12 200 Pekary et al. (1983) Antidepressant.
Melatonin 9.7–45.4 Luboshitzky (2002) Increases steroid effects, affects reproduction, induces sleep.
Relaxin 1240–73 000 Loumaye et al. (1980) Sperm motility, fertilization, implantation, uterine growth and accommodation.
Human chorionic gonadotropin 232.067–2510 de Medeiros (1992) Pregnancy maintenance.
Human placental lactogen Seppal a et al. (1985) Pregnancy maintenance.
Pregnancy-specific 1-glycoprotein Seppala et al. (1985) Pregnancy maintenance.
Placental protein 5 Seppala et al. (1985) Pregnancy maintenance.
Placental protein 12 Seppala et al. (1985) Pregnancy maintenance.
Placental protein 14 Seppala et al. (1985) Pregnancy maintenance.
Pregnancy-associated plasma protein Seppala et al. (1985) Pregnancy maintenance.
Serotonin Garcia-Hjarles (1990) Antidepressant.
Tyrosine van Overveld (2000) Precursor to dopamine, norepinephrine, epinephrine.
DOPA 40 230 Fait et al. (2001) Precursor to dopamine.
Norepinephrine 151 810 Fait et al. (2001) Attention, cognition, concentration.
B-Endorphin 154.7 Zalata et al. (1995) Immunosuppressant, opioid.
B-Endorphin 308 Davidson et al. (1989)
B-Endorphin 192 Singer et al. (1989)
Calcitonin 331 Davidson et al. (1989)
Calcitonin 754 Singer et al. (1989)
Enkephalin Sastry et al. (1991) Prevents acrosome activation, opioid, orgasm.
Substance P Sastry et al. (1991)
Cytokine interleukin 1a 26.1 Maegawa et al. (2002) Immunosuppressant.
Cytokine interleukin Maegawa et al. (2002) Immunosuppressant.
Cytokine interleukin 4 Maegawa et al. (2002) Immunosuppressant.
Cytokine interleukin 6 Maegawa et al. (2002) Immunosuppressant.
Cytokine interleukin 8 Maegawa et al. (2002) Immunosuppressant.
Tumor necrosis factor- a. Maegawa et al. (2002) Immunosuppressant
Interferon-y Maegawa et al. (2002) Immunosuppressant.
Granulocyte colony-stimulating factor Maegawa et al. (2002) Immunosuppressant.
Macrophage colony-stimulating factor Maegawa et al. (2002) Immunosuppressant.
Granulocyte elastase Maegawa et al. (2002) Immunosuppressant.
Carnitine Ruiz-Pesini et al. (2001)
Carnitine 256.92 Menchini-Fabris et al. (1984)

 

Additional Human Seminal Chemicals

which Manipulate Human Females:

Multiple sources. (See References)

Cells: PMN Leucocytes, Monocytes, Macrophages, Prostasomes.

Peptides: 5-nucleotidase, Tripeptide amides, Calcitonin, Glutathione,

Carnitine, Fibronectin, Bradykinin, Prostate specific antigen (PSA),

IL-8 H,  IL-12 H, sIL-2R, sIL-6R, TNF-alpha,

Transforming growth factor (TGF), Semenogelins, Phospholipases,

Angiotensin, Endothelin, LL-37, PAPP-A H, Transglutaminase,

Proteases, Immunoglobulins, Transferrin, Lactoferrin,

α2-macroglobulin, β2-microglobulin, Fc-receptor-binding protein,

ACTH H, Acid phosphatase, Prostate steroid binding protein (PSBP),

Albumin, Gastricsin, Leptin, Vitronectin, Lysozyme

Amino acids: Taurine, Polyamines Putrescine, Spermidine, Spermine

Catecholamines: Adrenaline, Noradrenaline, DOPAC, Eicosanoids

Alkaloids: Endogenous opiates

Steroids: Dihydroepiandrosterone

Sugars: Fructose

Salts: Bicarbonate, Ascorbate, Urate

Metals: Zinc

Note: This is by no means a comprehensive inventory.

pregnant gun photo

REFERENCES INCLUDE:

>Daly, Pure Lust, Harper Collins Publishers, 1984.

>Daly, Wickedary, Beacon Press, 1987.

>Burch & Gallup, “The Psychobiology of Sperm,” in

Female Infidelity and Paternal Uncertainty:

Evolutionary Perspectives on Anti-Cuckoldry Tactics,

Cambridge University Press, 2006.

>W. Rice, “Sexually Antagonistic Male Adaptation

Triggered by Experimental Arrest of Female Evolution,”

Nature, Vol. 381.

>Trevitt & Partridge, “The Cost of Receiving Sperm

in the Female Fruit Fly Drosophila melanogaster,”

Journal of Insect Physiology, Vol. 37, Issue 6.

>A. Poiana, “Complexity of Seminal Fluid:

A Review,” Behav Ecol, 2006.

>Andersson, et al., “Sexual Cooperation and

Conflict in Butterflies: a Male-Transferred

Anti-Aphrodisiac Reduces Harassment

of Recently Mated Females,”

Proceedings of The Royal Society of

London, Series B, Biological Sciences, 267.

>Fowler & Partrige, “A Cost of Mating

in Female Fruit Flies,” Nature, 338.

>Chapman, et al, “Cost of Mating

in Drosophila melanogaster Females

is Mediated by Male Accessory Gland

Products,” Nature, 373.

>Birkhead, Hosken, Pitnick, ed.,

Sperm Biology, AP Press.

>Linder & Rice, “Natural Selection

and Genetic Variation for

Female Resistance to Harm from Males,”

Journal of Evolutionary Biology, 2005.

>C. Panati, Panati’s Extrordinary Origins

of Everyday Things.

>C. Billhartz Gregorian,

“Mouth Tumors increase;

same virus causes cervical cancer,”

McClatchy Newspapers, October 15, 2008

>Arnqvist & Rowe, Sexual Conflict,

Princeton University Press.

>M. Majerus, Sex Wars:

Genes, Bacteria and Biased Sex Ratios,

Princeton University Press.

>S. Jones, Y: The Decent of Men,

Houghton-Mifflin Press.

>Wigby & Chapman, “Female Resistance to Male Harm

Evolves in Response to Manipulation of

Sexual Conflict,” Evolution, 2007.

>Xu & Wang, “Seminal Fluid

Reduces Female Longevity

and Stimulates Egg-production

and Sperm-trigger Oviposition in a Moth,”

Journal of Insect Physiology, 2011

>Civetta & Clark, “Correlated Effects

of Sperm Competition and

Post-Mating Female Mortality,”

Proceedings of the National Academy of Sciences

of the United Stated of America, 2000.